Best P21 (P021) 5 mg and 10mg Peptides GMP Factory

P21 (P021)

P21 (P021)

Other names:P021, Peptide 021

Peptide P21, also known as Cyclin-dependent kinase inhibitor one or CDK-interacting protein, is a nootropic peptide studied for its effects on improving neurogenesis. Animal studies show that P21 peptide can boost levels of BDNF, inhibiting the formation of Tau proteins and Amyloid plaques seen in Alzheimer’s disease through neurogenesis. At present, researchers are investigating the effects of P21 on the brain and how it could potentially combat disease. In this article, we’re going to explore P21 effects, benefits, and research studies. We’ll also show you the best place to buy P21 online for your own research study.

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Referenced Citations

[1]Li, Bin, Lukas Wanka, Julie Blanchard, Fei Liu, Muhammad Omar Chohan, Khalid Iqbal, and Inge Grundke-Iqbal. “Neurotrophic Peptides Incorporating Adamicetane Improve Learning and Memory, Promote Neurogenesis and Synaptic Plasticity in Mice.” FEBS Letters 584, no. 15 (June 30, 2010): 3359–3365. doi:10.1016/j.febslet.2010.06.025.

[2]Baazaoui, Narjes, and Khalid Iqbal. “Prevention of Dendritic and Synaptic Deficits and Cognitive Impairment with a Neurotrophic Compound.” Alzheimer’s Research & Therapy 9, no. 1 (June 27, 2017). doi:10.1186/s13195-017-0273-7.

[3]Bolognin, S., Buffelli, M., Puoliväli, J., & Iqbal, K. (2014). Rescue of cognitive-aging by administration of a neurogenic and/or neurotrophic compound. Neurobiology of aging, 35(9), 2134–2146. https://doi.org/10.1016/j.neurobiolaging.2014.02.017

[4]Khatoon, S., Chalbot, S., Bolognin, S., Puoliväli, J., & Iqbal, K. (2015). Elevated Tau Level in Aged Rat Cerebrospinal Fluid Reduced by Treatment with a Neurotrophic Compound. Journal of Alzheimer’s disease : JAD, 47(3), 557–564.

[5]Wei, W., Wang, Y., Liu, Y., Dai, C. L., Tung, Y. C., Liu, F., & Iqbal, K. (2020). Prenatal to early postnatal neurotrophic treatment prevents Alzheimer-like behavior and pathology in mice. Alzheimer’s research & therapy, 12(1), 102.

[6]Baazaoui, N., & Iqbal, K. (2017). Prevention of Amyloid-β and Tau Pathologies, Associated Neurodegeneration, and Cognitive Deficit by Early Treatment with a Neurotrophic Compound. Journal of Alzheimer’s disease : JAD, 58(1), 215–230.

[7]Wei, W., Liu, Y., Dai, C. L., Baazaoui, N., Tung, Y. C., Liu, F., & Iqbal, K. (2021). Neurotrophic Treatment Initiated During Early Postnatal Development Prevents the Alzheimer-Like Behavior and Synaptic Dysfunction. Journal of Alzheimer’s disease : JAD, 82(2), 631–646.

[8]Liu, Y., Wei, W., Baazaoui, N., Liu, F., & Iqbal, K. (2019). Inhibition of AMD-Like Pathology With a Neurotrophic Compound in Aged Rats and 3xTg-AD Mice. Frontiers in aging neuroscience, 11, 309.

[9]H. Chen, Y.-C.Tung, B. Li, K. lqbal, and l. Grundke-lqbal, “Trophic factors counteract elevated FGF-2-inducedinhibition of adult neurogenesis,” Neurobiol. Aging, vol. 28, no. 8,  pp. 1148-1162, Aug. 2007, doi:10.1016/j.neurobiolaging.2006.05.036

[10]E. Rockenstein, M. Mante, A. Adame, L. Crews, H. Moessler, and E. Masliah, “Effects of Cerebrolysin onneurogenesis in an APP transgenic model of Alzheimer’s disease,” Acta Neuropathol. (Berl.), vol. 113, no. 3, pp. 265-275, Mar. 2007, doi: 10.1007/s00401-006-0166-5.

[11]“Rat and Mice Weights | Animal Resources Centre.” http://www.arc.wagov.au/?page_id=125 (accessed Aug26,2020).

[12]K. lqbal, S. F. Kazim, S. Bolognin, and J. Blanchard, “Shifting balance from neurodegeneration to regenerationof the brain: a novel therapeutic approach to Alzheimer’sdisease and related neurodegenerative conditions,” Neural Regen. Res., vol.9, no. 16, pp. 1518-1519, Aug. 2014, doi: 10.4103/1673-5374.139477.

[13]B. Xu and X. Xie, “Neurotrophic factor control of satiety and body weight,” Nat. Rev. Neurosci., vol. 17, no. 5, pp.282-292, May 2016, doi: 10.1038/nrn.2016.24.

[14]M. K. Mohammad et al, “Olanzapine inhibits glycogensynthase kinase-3beta: an investigation by docking simulation and experimental validation,” Eur. J. Pharmacol., vol. 584, no. 1, pp. 185-191, Apr. 2008, doi:10.1016/j.ejphar.2008.01.019.

Author of this article:

Dr. Jean Zeng graduated from king’s college london Faculty of Life Sciences & Medicine. 

Scientific Journal paper Author:

1.Mohammad K. Mohammad

Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Amman 11942, Jordan

2.Bin Li

Department of Neurochemistry, NYS Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA

3.Lukas Wanka

Department of Neurochemistry, NYS Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA

In no way does this doctor/scientist endorse or advocate the purchase, sale, or use of this product for any reason. peptide.ltd has no affiliation or relationship, implied or otherwise, with this physician. The purpose of citing this doctor is to acknowledge, acknowledge and commend the exhaustive research and development work done by the scientists working on this peptide.

Author of this article:

Dr. Jean Zeng graduated from king's college london Faculty of Life Sciences & Medicine.

Scientific Journal paper Author:

Stephen C. Bain
Diabetes Research Group, Swansea University Medical School, Swansea, SA2 8PP, UK
Department of Diabetes and Endocrinology, Singleton Hospital, Swansea Bay University Health Board, Swansea, SA2 8QA, UK

In no way does this doctor/scientist endorse or advocate the purchase, sale, or use of this product for any reason. Polypeptide.ltd has no affiliation or relationship, implied or otherwise, with this physician. The purpose of citing this doctor is to acknowledge, acknowledge and commend the exhaustive research and development work done by the scientists working on this peptide.